Insulin-like Growth Factor-1 (IGF-1)
IGF-1 promotes systemic (system wide) growth and has growth stimulating effects on almost every cell in the body. Especially cartilage, bone, liver, skeletal muscle, kidneys, nerves, skin, and lungs. IGF-1 plays an critical part in childhood growth and continues to have anabolic effects for an individuals entire life cycle. IGF-1 is one of the most potent natural activators of the AKT signalling pathway. The AKT signaling pathway stimulates cell growth generation, and is a potent inhibitor of cell death.
How to boost IGF-1 production naturally:
Naturally increase GH production.
Follow a resistance training program aimed at hypertrophy and progressive overload (muscle growth).
Research shows that compound lifts trigger greater hormone responses and that adding a pause (tempo) into a lift will allow IGF-1 to exert a greater anabolic effect.
Perform high intensity interval cardio (HIIT) instead of steady state cardio.
Supplement with an amino acid that contain arginine, ornithine and betaine.
Supplement with magnesium.
Supplement or increase your dietary intake of phosphatidylcholines (PC), a class of phospholipids found in egg yolk and soy beans.
GH stimulates IGF-1 release from the liver. Thyroid hormone stimulates the secretion of GH and also increase the number of GH receptors in the liver increasing IGF-1 serum levels.